Faculty Advisor(s)

Michelle Adams

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Abstract

Contrast-Enhanced Spectral Mammography (CESM) is an advanced breast imaging technique that enhances the detection and characterization of breast lesions, more specifically in patients with dense breast tissue where conventional mammography is limited. This research explores the principles, clinical applications, advantages, and limitations of CESM. The technique utilizes dual-energy imaging combined with intravenous iodinated contrast to highlight areas of increased vascularity, which are often seen with malignancy. CESM provides both anatomical and functional imaging in one efficient examination. Studies demonstrate that CESM offers higher sensitivity and comparable specificity to traditional mammography, with diagnostic performance approaching that of breast MRI while being more cost-effective and accessible. Clinical applications include lesion detection, preoperative staging, and monitoring treatment response. Despite its benefits, CESM does present some limitations such as increased radiation dose and risks associated with contrast administration. Emerging advancements in artificial intelligence are further enhancing diagnostic accuracy and workflow efficiency. The findings suggest that CESM is a valuable tool in breast cancer imaging and has the potential to greatly improve clinical decision-making. Future research should focus on optimizing patient selection, minimizing risks, and integrating artificial intelligence to further advance the capabilities of CESM.

Publication Date

2026

Document Type

Poster

Department

Medical Imaging

Keywords

contrast-enhanced spectral mammography, breast cancer, dense breast tissue, dual-energy imaging, diagnostic imaging, artificial intelligence

Disciplines

Medicine and Health Sciences

Contrast-Enhanced Spectral Mammography

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